Katalin Karikó

    1955 – Present

    Biochemistry
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    Who is Katalin Karikó?

    Katalin Karikó (born 1955) is a Hungarian-American biochemist. Her work with Drew Weissman on modified mRNA made the COVID-19 vaccines possible, and the two shared the 2023 Nobel Prize in Physiology or Medicine.

    A lab bench with pipettes and sample vials, the kind of work behind Katalin Karikó's mRNA research
    A lab bench with pipettes and sample vials, the kind of work behind Katalin Karikó's mRNA research

    Key Achievement

    Pioneered mRNA technology that enabled COVID-19 vaccines

    Her story

    Hungarian biochemist whose decades of research on mRNA technology laid the foundation for COVID-19 vaccines, faced repeated rejection and demotion before her work saved millions of lives, Nobel Prize winner 2023.

    Questions people ask about Katalin Karikó

    What did Katalin Karikó discover?

    With Drew Weissman she found that changing one building block of mRNA (uridine) stops the body's immune system from attacking it. This made mRNA usable as a medicine.

    Did Katalin Karikó win a Nobel Prize?

    Yes. She and Drew Weissman won the 2023 Nobel Prize in Physiology or Medicine for discoveries that enabled effective mRNA vaccines against COVID-19.

    How did Katalin Karikó's work lead to COVID vaccines?

    Their modified-mRNA method was used by BioNTech/Pfizer and Moderna to build COVID-19 vaccines quickly in 2020.

    Did Katalin Karikó face setbacks?

    Yes. For years her mRNA research struggled to get funding, and she was demoted at the University of Pennsylvania. She kept going anyway.

    Sources & further reading

    Brass gears and punched cards, the technology behind Babbage's Analytical Engine

    Ada Lovelace

    1815 - 1852

    Mathematics & Computing

    Mathematician recognized as the first computer programmer for her work on Charles Babbage's Analytical Engine. She envisioned computers beyond pure calculation.

    A 1950s low-temperature physics lab, like the one used for the Wu experiment

    Chien-Shiung Wu

    1912 - 1997

    Nuclear Physics

    Experimental physicist who made significant contributions to nuclear physics. Her work disproved the law of conservation of parity, earning others a Nobel Prize.

    Courtyard of the al-Qarawiyyin in Fez, the learning centre Fatima al-Fihri founded

    Fatima al-Fihri

    800 - 880

    Education & Scholarship

    Moroccan scholar who founded the University of al-Qarawiyyin in 859 CE, recognized as the world's oldest existing, continually operating university.